Ellen Landes specializes in helping runners optimize their performance and overall well-being through a realistic approach to nutrition. As a registered dietitian and a certified personal trainer, she brings a comprehensive understanding of evidence-based nutrition and exercise science to both her practice and her writing. Learn more at her website, LinkedIn, or Instagram.n”},”avatar”:{“title”:””,”width”:500,”height”:500,”src”:”https://post.healthline.com/wp-content/uploads/2022/01/Ellen-Landes-MS-RDN-CPT-500×500-Bio.png”}}],”medicalReviewers”:[{“id”:5334,”name”:{“display”:”Jerlyn Jones, MS MPA RDN LD CLT”,”first”:”Jerlyn”,”last”:”Jones, MS MPA RDN LD CLT”},”userLogin”:”jjones”,”links”:{“website”:”https://www.thelifestyledietitian.com”,”facebook”:”www.facebook.com/thelifestyledietitian/”,”linkedin”:”https://wwww./linkedin.com/in/JerlynJones”,”twitter”:”https://twitter.com/jerlynnutrition”,”instagram”:”https://www.instagram.com/thelifestyledietitian_/”,”tiktok”:””},”link”:”/reviewers/jerlyn-jones-ms-mpa-rdn-ld-clt”,”email”:”thelifestyledietitian@gmail.com”,”type”:{“value”:”medical_reviewer”,”label”:”Medical Advisor”},”nid”:””,”specialties”:[{“name”:”Nutrition”}],”guestTitle”:””,”bio”:{“text”:” Jerlyn Jones is a registered dietitian nutritionist, national media spokesperson, nutrition writer, and owner of The Lifestyle Dietitian LLC, an Atlanta-based nutrition consulting practice. She specializes in integrative nutrition with an emphasis on food sensitivities, digestive problems, and women’s health.n Educationn Certificationsn Professional Accomplishmentsn Affiliationsn Culturelle is a well-known brand of probiotics and is one of the best overall probiotic supplements thanks to its formulation and high CFU count. Plus, it doesn’t need to be refrigerated. One capsule of Culturelle Digestive Daily Probiotic has 10 billion CFUs of Lactobacillus rhamnosus GG, a probiotic strain that may benefit a number of health conditions, such as diarrhea and irritable bowel syndrome (IBS). This supplement also contains 200 milligrams (mg) of the prebiotic inulin, which fuels beneficial gut bacteria. Culturelle guarantees that the stated number of CFUs on the box is viable through the expiration date of the product, something the National Institutes of Health (NIH) recommends customers look out for. While products are not routinely tested for purity and potency by a third-party lab, the company states that it takes multiple measures to ensure quality and safety. Additionally, Culturelle probiotics have been used in multiple clinical studies, and the company’s processes are audited regularly by NSF International. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”f8cc03626bad11c0ada6b9e3d767179d66536ced8469b5590f3d17f1bb566f45″,”variantId”:”5dc41278-61fd-4048-ba77-92e4ec455104″,”pid”:”culturelle_womenshealthybalance_textlink_38745″,”showDisclaimer”:false,”productName”:”Culturelle Women’s 4-in-1 Protection”,”productBrand”:”Culturelle”,”price”:”27.49″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1 capsule per day”},{“label”:”Certifications”,”value”:”none”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Price”,”value”:”$$”}],”destinationStore”:”Culturelle”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”30 per container”},{“label”:”Strains”,”value”:”Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus rhamnosus GG, Lactobacillus gasseri LBV 150N, Lactobacillus jensenii LBV 116″},{“label”:”CFU count”,”value”:”15 billion”}],”pros”:[“supports vaginal and urinary health”,”doesn't need refrigeration”,”gluten-free and dairy-free”,”rigorous quality and safety standards”,”packaged to ensure CFU count until end of shelf life”,”contains clinically studied strains”,”includes prebiotics”],”cons”:[“not third-party tested for purity and potency”,”may not be suitable for those following a vegan diet”],”ctaUrl”:”https://activation.healthline.com/api/member-offers/8356/redirect?lp=328&tc=120226&subid2=%2Fnutrition%2Fbest-probiotic-supplement&subid=culturelle_womenshealthybalance_textlink_38745″,”ctaText”:”SHOP NOW AT CULTURELLE”,”rating”:”4.6″,”numberOfRatings”:”(124+) from Culturelle”,”superlative”:”Best probiotic supplement for women”,”imgSrc”:”https://post.healthline.com/wp-content/uploads/2023/07/Culturelle-Womens-4-in-1-Protection-Capsules.png”,”imgAlt”:”Culturelle Probiotics Women’s 4 in 1 Protection”,”healthlineReview”:” Each serving of Culturelle 4-in-1 Protection contains 15 billion CFUs of the probiotic strains Lactobacillus rhamnosus GG, Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus gasseri LBV 150, and Lactobacillus jensenii LBV 116, all of which are important for women’s health. Lactobacillus rhamnosus GG promotes healthy digestion, while the rest of the included stains, such as Lactobacillus gasseri, benefit vaginal and urinary health. These strains help keep your vaginal bacteria population healthy and may also help protect against urinary tract infections by preventing the invasion of potentially harmful pathogens and encouraging a balanced environment in the vagina and urinary tract. The supplement also includes a proprietary blend of prebiotics. You can find more of our picks of the best probiotics for women here.”,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”a094d3b7c23b8b8f6dc583859bb82d3b7299300c8973f2ea95ff0640fb37c61e”,”variantId”:”9442e410-2aea-424d-8b7d-6849391dfe54″,”pid”:””,”showDisclaimer”:false,”productName”:”Align Extra Strength Probiotic Capsules”,”productBrand”:”Align probiotic”,”price”:”49.97″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1 capsule per day”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Certifications”,”value”:”none”},{“label”:”Price”,”value”:”$$$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”21 per container”},{“label”:”Strains”,”value”:”Bifidobacterium longum subsp. longum”},{“label”:”CFU count”,”value”:”5 billion”}],”pros”:[“travel-friendly”,”formulated to relieve digestive issues”,”contains a clinically tested strain “,”DNA tested to confirm identity”],”cons”:[“may not be appropriate for those with lactose intolerance”,”not suitable for vegan diets”,”expensive”,”unclear whether product is third-party tested for purity and potency”],”ctaUrl”:”https://www.amazon.com/dp/B08B7BWHJ8?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4.7″,”numberOfRatings”:”(6.8k+) from Amazon”,”superlative”:”Best probiotic supplement for IBS”,”imgSrc”:”https://i0.wp.com/post.healthline.com/wp-content/uploads/2021/10/1689068-Align-Extra-Strength.png?w=525″,”imgAlt”:”Align Extra Strength Probiotic”,”healthlineReview”:” Align is a physician-trusted brand that contains Bifidobacterium longum 35624, formerly known as Bifidobacterium infantis 35624, a probiotic strain that has been researched for its role in digestive health, including IBS symptoms. This product’s label states that each capsule contains 5 billion live bacteria at the time of manufacturing and 50 million CFUs until the “best by” date. Because it doesn’t require refrigeration, it’s a good option if you travel often or prefer not to worry about storing your probiotic supplement in the fridge. Note that Align contains trace amounts of lactose, so it may not be appropriate for those with severe lactose intolerance. According to the company, Align Probiotic is DNA tested to confirm that it contains Bifidobacterium longum 35624. However, it’s unclear whether testing is performed in-house or by a third-party organization. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”115ead6b992c9a6a9b50efd6c9a944f54e07db08e2629568a404a9a622ef8b4f”,”variantId”:”cbad2604-9b3a-4d81-8f7f-2a12b9284071″,”pid”:””,”showDisclaimer”:false,”productName”:”Bio-Kult”,”productBrand”:”Bio-Kult”,”price”:”20.97″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1–2 capsules once or twice per day”},{“label”:”Certifications”,”value”:”Vegetarian Society Approved, non-GMO”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Price”,”value”:”$$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”30, 60, or 120 per container”},{“label”:”Strains”,”value”:”Bacillus subtilis PXN 21, Bifodobacterium bifidum PXN 23, Bifidobacterium breve PXN 25, Bifidobacterium infantis PXN 27, Bifidobacterium longum PXN 30, Lactobacillus acidophilus PXN 35, Lactobacillus delbrueckii ssp. bulgaricus PXN 39, Lactobacillus casei PXN 37, Lactobacillus plantarum PXN 47, Lactobacillus rhamnosus PXN 54, Lactobacillus helveticus PXN 45, Lactobacillus salivarius PXN 57, Lactococcus lactis ssp. lactis PXN 63, Streptococcus thermophilus PXN 66″},{“label”:”CFU count”,”value”:”2 billion”}],”pros”:[“stored at room temperature”,”relatively affordable”,”suitable for all ages”,”supports men's health”],”cons”:[“not appropriate for those with severe allergy to milk proteins”,”not suitable for vegan diets”,”unclear whether product is third-party tested for purity and potency”],”ctaUrl”:”https://www.amazon.com/dp/B004SGO4DG?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4.6″,”numberOfRatings”:”(7.7k+) from Amazon”,”superlative”:”Best probiotic supplement for men”,”imgSrc”:”https://post.healthline.com/wp-content/uploads/2021/11/1741421-Bio-Kult.png?w=525″,”imgAlt”:”Bio-Kult”,”healthlineReview”:” Bio-Kult contains 14 probiotic strains that may be beneficial for men’s health, including Lactobacillus acidophilus, Streptococcus thermophilus, and Bifidobacterium longum. Additionally, some research suggests that supporting a healthy microbiome by taking a high quality probiotic supplement, such as Bio-Kult, may help protect against prostate cancer, the most common form of cancer among men in the United States. Each Bio-Kult capsule contains a minimum of 2 billion microorganisms, and Bio-Kult guarantees that the total bacteria count is viable until the end of the product’s shelf life. Each probiotic strain in Bio-Kult is microencapsulated and individually freeze-dried. This protects the probiotics from stomach acid and allows the product to be stored at room temperature. Bio-Kult is not appropriate for those with a severe allergy to milk proteins, but it is safe for those with lactose intolerance. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”481cd116ad8aee5b35f2631fd3a251dcb9b8f011be69931a456d96e361bba986″,”variantId”:”4ef05083-bad4-4b8b-82a1-8d12cfc1a96e”,”pid”:””,”showDisclaimer”:false,”productName”:”Jarrow Formulas Jarro-Dophilus EPS Capsules”,”productBrand”:”Jarrow Formulas”,”price”:”40.95″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”2 capsules per day”},{“label”:”Certifications”,”value”:”third-party tested for purity and potency”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Price”,”value”:”$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”60 or 30 per container”},{“label”:”Strains”,”value”:”Lacticaseibacillus rhamnosus, Lactobacillus helveticus, Pediococcus acidilactici, Lacticaseibacillus casei, Bifidobacterium longum, Lactiplantibacillus plantarum, Bifidobacterium breve, Lactococcus lactis subsp. lactis”},{“label”:”CFU count”,”value”:”10 billion”}],”pros”:[“no refrigeration necessary”,”third-party tested for purity and potency”,”relatively affordable”],”cons”:[“not suitable for vegan diets”],”ctaUrl”:”https://www.amazon.com/dp/B0013OUKTS?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4.7″,”numberOfRatings”:”(2.5k+) from Amazon”,”superlative”:”Best affordable probiotic supplement”,”imgSrc”:”https://post.healthline.com/wp-content/uploads/2023/05/Jarrow-Formulas-Jarro-Dophilus-EPS-10-Billion.png”,”imgAlt”:”Jarrow Formulas Jarro-Dophilus EPS”,”healthlineReview”:” Jarrow Formulas Jarro-Dophilus EPS contains eight probiotic species from six genera: Lactobacillus, Bifidobacterium, Lacticaseibacillus, Lactiplantibacillus, Lactococcus, and Pediococcus. It’s also one of the most affordable options. The capsules have an enteric coating, which is a barrier that helps minimize degradation in the stomach. Some studies show that enteric-coated probiotics are more effective than non-enteric-coated probiotics. A 2019 study found that enteric coating led to a 20‐ to 40‐fold increase in the delivery of viable probiotics to the small intestine. If the product is stored properly — at room temperature in a cool, dry environment — the 5 billion CFU count per capsule is guaranteed through the “best used before” date. Jarrow Formulas products are tested by third-party labs that are accredited by the U.S. Department of Agriculture (USDA). “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”65ece1b27a89a44d0dfb8e1ebd07da6d80767a14bf0a2d8d1fc4e9544c477707″,”variantId”:”28fc4e22-d077-4bf6-b035-37b44680702d”,”pid”:””,”showDisclaimer”:false,”productName”:”Garden of Life Dr. Formulated Probiotics Once Daily Capsules”,”productBrand”:”Garden of Life”,”price”:”30.98″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1 capsule per day”},{“label”:”Certifications”,”value”:”non-GMO verified, certified NSF Gluten-Free, third-party tested for purity and potency”},{“label”:”Shelf-stable”,”value”:”no”},{“label”:”Price”,”value”:”$$$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”30 per container”},{“label”:”Strains”,”value”:”Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus gasseri, Lactobacillus paracasei, Bifidobacterium lactis, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum”},{“label”:”CFU count”,”value”:”30 billion”}],”pros”:[“CFU count guaranteed through best-use date when product is stored properly”,”dairy-free”,”contains strains that may promote weight loss”,”third-party tested for purity and potency”],”cons”:[“not suitable for travel, as it requires refrigeration”,”expensive”,”not suitable for those with severe food allergies”,”not vegan-friendly”],”ctaUrl”:”https://www.amazon.com/dp/B010MAD4ZK?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4.6″,”numberOfRatings”:”(1k+) from Amazon”,”superlative”:”Best probiotic supplement for weight loss”,”imgSrc”:”https://i0.wp.com/post.healthline.com/wp-content/uploads/2021/10/1689068-Garden-of-Life-Dr-Formulated-Probiotics-Once-Daily.png?w=525″,”imgAlt”:”Garden of Life Dr. Formulated Probiotics Once Daily”,”healthlineReview”:” Research shows that people who are overweight are more likely to have dysbiosis (an imbalance in gut bacteria) and lower bacterial diversity than people who are not. This may increase hunger and increase energy storage in fat tissues, which contributes to weight gain. Taking a probiotic supplement containing specific probiotic strains, such as Lactobacillus gasseri, L. rhamnosus, and L. plantarum, may help promote weight loss in several ways, including by decreasing gut permeability, reducing inflammation, and increasing bacterial diversity. Garden of Life Dr. Formulated Probiotics Once Daily, 30 Billion CFUs provides 30 billion CFUs of 14 probiotic strains, including Lactobacillus gasseri and L. rhamnosus, which could help support weight loss. Garden of Life guarantees the CFU count through the end of the product’s “best use” date if it’s stored properly. This supplement keeps best in the refrigerator. According to the company, Garden of Life supplements are third-party tested. However. the company does not disclose the name of the testing organization. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”0bdae2235ba85da25a86d8c7febd791f452acfd02f2948c9ade97b5725355977″,”variantId”:”4dc57bad-5e07-4572-99e0-4f4ebc8698a0″,”pid”:””,”showDisclaimer”:false,”productName”:”NOW Probiotic-10 Capsules”,”productBrand”:”Now”,”price”:”24.34″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1 capsule, once or twice per day”},{“label”:”Certifications”,”value”:”CGMP certified, Strain Verified, UL Solutions Certified”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Price”,”value”:”$$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”30, 50, or 100 per container”},{“label”:”Strains”,”value”:”Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus paracasei, Bifidobacterium breve, Streptocous thermophilus, Lactobacillus salivarius, Bifidobacterium longum “},{“label”:”CFU count”,”value”:”25 billion”}],”pros”:[“processed in an allergen-free facility”,”UL Solutions-certified”,”delivers a potency of at least 25 billion CFUs through the best-by date”,”uses DNA fingerprinting technology “,”may support a strong immune system”],”cons”:[“not suitable for vegan diets”],”ctaUrl”:”https://www.amazon.com/dp/B00L1GHMN0?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4.6″,”numberOfRatings”:”(11.1k+) from Amazon”,”superlative”:”Best allergy-friendly probiotic supplement”,”imgSrc”:”https://i0.wp.com/post.healthline.com/wp-content/uploads/2021/10/1689068-NOW-Probiotic-10-25-Billion.png?w=525″,”imgAlt”:”NOW Probiotic-10″,”healthlineReview”:” NOW Probiotic-10 25 Billion is a blend of 10 probiotics, including Lactobacillus acidophilus, Bifidobacterium lactis, and Lactobacillus rhamnosus. Many of the strains it contains have been shown to support immune health. This product is formulated to deliver a potency of at least 25 billion CFUs through the “best by” date. NOW uses DNA fingerprinting technology to guarantee the identity, potency, and purity of the bacterial strains used in its probiotic products. This testing also helps identify potential bacterial contaminants in the products prior to manufacturing. Additionally, NOW’s facilities are certified by UL Solutions (previously Underwriters Laboratories), an independent certification safety company that ensures safe manufacturing and storage practices. This probiotic is processed in an allergen-free facility, so it’s suitable for those with allergies. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”61dacb62f21f853ba9dadcca401be6b3793f5405dbb9557183b375c320a7e98e”,”variantId”:”721b2ced-1c16-4974-801a-d5bdcce3f39f”,”pid”:””,”showDisclaimer”:false,”productName”:”Klaire Labs Ther-Biotic Pro IBS Relief Capsules”,”productBrand”:”Klaire Labs”,”price”:”34.99″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1 capsule, once or twice per day”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Certifications”,”value”:”Monash University Low FODMAP Certified, NSF Certified”},{“label”:”Price”,”value”:”$$$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”21 or 42 per container”},{“label”:”Strains”,”value”:”Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus plantarum”},{“label”:”CFU count”,”value”:”20 billion”}],”pros”:[“contains probiotics and prebiotics”,”contains strains that may help manage IBS symptoms”,”does not require refrigeration”,”free from allergens”,”NSF Certified”],”cons”:[“expensive”,”not suitable for vegan diets”,”not suitable for people who don't tolerate prebiotics well”],”ctaUrl”:”https://www.amazon.com/dp/B09F2F69W4?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4″,”numberOfRatings”:”(90+) from Amazon”,”superlative”:”Best pre- and probiotic supplement”,”imgSrc”:”https://i0.wp.com/post.healthline.com/wp-content/uploads/2022/02/1689068-Klaire-Labs-Ther-Biotic-Pro-IBS-Relief.png?w=525″,”imgAlt”:”Klaire Labs Ther-Biotic Pro IBS Relief”,”healthlineReview”:” Klaire Labs Ther-Biotic Pro contains a blend of probiotics and a prebiotic. Specifically, it contains Lactobacillus and Bifidobacterium probiotic strains, both of which have been shown to help relieve IBS-related symptoms such as abdominal pain, constipation, and diarrhea, though more research is still needed. It also includes partially hydrolyzed guar gum, a prebiotic that feeds the good bacteria in your gut. A 2019 study found that 5 grams of partially hydrolyzed guar gum was effective `in improving stool form in adults with IBS-D over the course of 12 weeks, but more research is needed. This product is free from common allergens, though it’s unclear whether there’s a risk of cross-contamination. Additionally, the supplement doesn’t require refrigeration, but storing it in the refrigerator may extend its shelf life. Klaire Labs products are processed in a facility that follows the CGMPs put in place by the FDA and is certified by NSF International. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”6f07f217fa2158fd6b0ff7b4b1bdbbdc2d899e40ec786e8b4a4d63ccdfe0559d”,”variantId”:”c87c839a-475b-4a42-8c34-784f86e54bab”,”pid”:”optumstore_thorne_florasport_20bprobiotic_textlink_38649″,”showDisclaimer”:false,”productName”:”Thorne FloraSport 20B Probiotic Capsules”,”productBrand”:”Thorne”,”price”:”37″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”1 capsule, once or twice per day”},{“label”:”Certifications”,”value”:”NSF Certified for Sport”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Price”,”value”:”$$$”}],”destinationStore”:”Optum Store”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”30 per container”},{“label”:”Strains”,”value”:”Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus paracasei”},{“label”:”CFU count”,”value”:”20 billion”}],”pros”:[“packaged in temperature-resistant blister packs — no refrigeration required”,”formulated for athletes, active individuals, and travelers”,”NSF Certified for Sport”],”cons”:[“expensive”,”may not be suitable for those following a vegan diet”],”ctaUrl”:”https://activation.healthline.com/api/member-offers/7524/redirect?lp=328&tc=120226&subid2=%2Fnutrition%2Fbest-probiotic-supplement&subid=optumstore_thorne_florasport_20bprobiotic_textlink_38649″,”ctaText”:”SHOP NOW AT OPTUM STORE”,”rating”:”0″,”numberOfRatings”:””,”superlative”:”Best probiotic supplement for athletes”,”imgSrc”:”https://i0.wp.com/post.healthline.com/wp-content/uploads/2022/02/1689068-Thorne-FloraSport-20B.png?w=525″,”imgAlt”:”Thorn FloraSport 20B Probiotic”,”healthlineReview”:” Thorne FloraSport 20B contains 20 billion CFUs from 3 probiotic strains. It’s formulated specifically for individuals who are under stress, such as athletes, as it’s meant to support both the digestive and immune systems. While exercise has many benefits, engaging in regular high intensity workouts can take a toll on your body’s immune response. This probiotic from Thorne contains Lactobacillus acidophilus and Bifidobacterium lactis, both of which have been shown to support immune health and could be beneficial for athletes and other active individuals. Refrigeration isn’t required, as the capsules are packaged in temperature-resistant blister packs, making this a great option for traveling. Additionally, this probiotic supplement is certified gluten-free and NSF Certified for Sport — a third-party certification that ensures products are free of substances banned in competitive sports. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”42c27bd1f6959c36dfcf23b9cac92a684543a799bbbd0a104ccbc9aa4bcbb146″,”variantId”:”44e2320e-b4c8-450d-9aa3-5b6e0d7da0c9″,”pid”:””,”showDisclaimer”:false,”productName”:”Florastor Daily Probiotic Capsules”,”productBrand”:”Florastor”,”price”:”60.13″,”discount”:””,”highlights”:[{“label”:”Dose”,”value”:”2 capsules, once or twice per day”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Certifications”,”value”:”none”},{“label”:”Price”,”value”:”$$$”}],”destinationStore”:”Amazon”,”productDetails”:[{“label”:”Form”,”value”:”capsule”},{“label”:”Number of servings”,”value”:”27 or 50 per container”},{“label”:”Strains”,”value”:”Saccharomyces boulardii”},{“label”:”CFU count”,”value”:”250 mg of Saccharomyces boulardii CNCM I-745″}],”pros”:[“high customer rating”,”no refrigeration required”,”contains probiotic strain that may be helpful for antibiotic-associated and acute diarrhea”],”cons”:[“not appropriate for those with an allergy to milk proteins “,”unclear if third-party tested for purity and potency”],”ctaUrl”:”https://www.amazon.com/dp/B01NB0G1V8?tag=healthline-subtag-20″,”ctaText”:”SHOP NOW AT AMAZON”,”rating”:”4.7″,”numberOfRatings”:”(9.1k+) from Amazon”,”superlative”:”Best probiotic supplement for diarrhea”,”imgSrc”:”https://i0.wp.com/post.healthline.com/wp-content/uploads/2022/02/1689068-Florastor-Daily-Probiotic-Supplement-for-Women.png?w=525″,”imgAlt”:”Florastor Daily Probiotic”,”healthlineReview”:” Each capsule of Florastor Daily Probiotic provides 250 mg of Saccharomyces boulardii, a probiotic yeast that may be effective in managing symptoms of inflammatory bowel disease (IBD). The strain has also been shown to help with diarrhea, especially antibiotic-associated or acute diarrhea (15, 16). At time of publish, Florastor Daily Probiotic has a 4.7 out of 5-star rating on Amazon and more than 9,000 total reviews. Customers note that the probiotic is effective for reducing gas and bloating, though many also feel that it’s a bit too expensive. The supplement comes in a vegetarian capsule and is non-GMO and gluten-free. However, because it contains lactose, it’s not suitable for those who have a dairy allergy. It’s unclear whether these probiotics are tested to ensure purity and potency. While Florastor doesn’t mention third-party testing on the company’s website, the product is sold by CVS, which requires third-party testing on all of its dietary supplements. “,”handsOnReview”:””,”reviewAuthorName”:””,”bgColor”:””},{“id”:”ce449d6c6486fbc05a30de3f3514cc2f7079ce12216cb65eca87334fca976807″,”variantId”:”d1a148c3-ab25-4150-9071-97b141af5537″,”pid”:”Ritual_Synbiotic_Textlink_38399″,”showDisclaimer”:false,”productName”:”Ritual Synbiotic+ Probiotic Capsules”,”productBrand”:”Ritual”,”price”:”54″,”discount”:”Use code “HEALTHLINE” for 25% off your first month”,”highlights”:[{“label”:”Dose”,”value”:”1 capsule per day”},{“label”:”Shelf-stable”,”value”:”yes”},{“label”:”Certifications”,”value”:”third-party tested for purity and potency, Non-GMO Project Verified, Made Traceable”},{“label”:”Price”,”value”:”$$$”}],”destinationStore”:”Ritual”,”productDetails”:[{“label”:”Form”,”value”:”capsules”},{“label”:”Number of servings”,”value”:”30 per container”},{“label”:”Strains”,”value”:”Lactobacillus rhamnosus LGG, Bifidobacterium animalis ssp. lactis BB-12″},{“label”:”CFU count”,”value”:”11 billion”}],”pros”:[“third-party tested for purity and potency”,”vegan-friendly”,”no refrigeration required “,”delayed-release capsule design”,”good for people interested in a pre-, pro-, and postbiotic”,”not suitable for people who don't tolerate prebiotics well”],”cons”:[“expensive”],”ctaUrl”:”https://activation.healthline.com/api/member-offers/7416/redirect?lp=328&tc=120226&subid2=%2Fnutrition%2Fbest-probiotic-supplement&subid=Ritual_Synbiotic_Textlink_38399″,”ctaText”:”SHOP NOW AT RITUAL”,”rating”:”0″,”numberOfRatings”:””,”superlative”:”Best probiotic subscription”,”imgSrc”:”https://post.healthline.com/wp-content/uploads/2022/07/1972044-Ritual-Synbiotic-with-bg.png?w=525″,”imgAlt”:”Ritual Synbiotic+ Probiotic Capsules”,”healthlineReview”:” Ritual is a subscription-based supplement company best known for its multivitamins. However, the company also offers Synbiotic+, a probiotic that stands out from others on the market because it contains pre-, pro-, and postbiotics. Postbiotics are bioactive compounds that bacteria secrete, often through fermentation. While postbiotics are believed to offer some health benefits, research on the subject is limited. Ritual’s Synbiotic+ contains probiotic strains, such as Lactobacillus rhamnosus, that may be beneficial for people with IBS, though more research is needed. The company conducted a test-tube study that suggested Synbiotic+ could support gut barrier function and increase the growth of beneficial bacteria. But keep in mind that because Ritual funded the study, there is a risk of bias. “,”handsOnReview”:” “I’ve struggled with digestive issues for years and was excited to try out Synbiotic+ as a possible replacement for the expensive pre- and probiotics that I was taking. “I’ve been taking the supplement for 3 weeks and haven’t experienced an adjustment period or negative side effects. So far, it seems to be helping with my bloating, and the pills’ minty-fresh flavor is fantastic. “Overall, I’ve had a great experience and will be replacing my old supplements with Ritual Synbiotic+” — Christy Snyder, Editor II Read more about Ritual in our expert review. “,”reviewAuthorName”:”Christy Snyder, Editor II”,”bgColor”:””}],”relatedStories”:false,”wellness”:{“title”:”wellness reads”,”coverImageUrl”:”/hlcmsresource/images/frontend-static/sidebar-wellness/7354-wellness_reads_option2_600x260-rightrail.jpg”,”items”:[{“title”:{“text”:”10 Exercises to Tone Every Inch of Your Body”,”matches”:”Tone Every Inch”},”url”:”/health/fitness-exercise/10-best-exercises-everyday”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2020/07/7040-hispanic_female_exercise-732×549-thumbnail-732×549.jpg”},{“title”:{“text”:”For a Longer Life and Happier Gut, Eat More Fiber”,”matches”:”Longer Life”},”url”:”/health/food-nutrition/fiber-diet-good-for-gut-and-health”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2018/01/oatmeal-granola-berries-fiber-732×549-thumbnail-732×549.jpg”},{“title”:{“text”:”Top 6 Benefits of Taking Collagen Supplements”,”matches”:”Collagen”},”url”:”/nutrition/collagen-benefits”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2020/02/mirror-beauty-skin-732×549-thumbnail-732×549.jpg”},{“title”:{“text”:”6 Ways to Boost Your Coffee with Vitamins and Antioxidants”,”matches”:”Boost Your Coffee”},”url”:”/health/food-nutrition/vitamin-coffee-natural-boost”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2020/08/Hands_Coffee_Cinnamon_732x549-thumbnail-732×549.jpg”},{“title”:{“text”:”The 3-Day Fix for Energy”,”matches”:”3-Day Fix”},”url”:”/health/healthy-sleep/guide-fix-fatigue-and-sleepiness”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2018/03/male-walking-outdoors-poc-happy-732×549-thumbnail-732×549.jpg”}]},”infiniteScroll”:true,”totalScrollArticles”:[{“title”:[“When’s the Best Time to Take Probiotics?”],”text”:[“Probiotics contain live microorganisms that can support and enhance your healthy gut bacteria. 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She works with health and wellness brands and the media to share evidence-based health and nutrition information that inspires readers to eat well, age gracefully, and live life to the fullest. When she’s not writing, you’ll find her cooking up something tasty for her food and nutrition website Craving Something Healthy, or hiking with one eye on the mountain views and the other watching out for rattlesnakes. To read more about her work or connect with her, visit her website, LinkedIn, or Instagram.n”},”avatar”:{“title”:””,”width”:500,”height”:500,”src”:”https://post.healthline.com/wp-content/uploads/2021/12/Anne-Danahy-500×500-Bio.png”}}],”reviewedByHeader”:”By”},{“title”:[“11 Probiotic Foods That Are Super Healthy”],”text”:[“Eating fermented foods with live probiotics can have powerful benefits for your body and brain. 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Warwick, R.D., CDE”,”reviewerImage”:{“path”:”https://post.healthline.com/wp-content/uploads/2022/01/Kathy-Warwick-500×500-Bio.png”,”width”:200,”height”:200,”altText”:””},”specialties”:[]},”isNutrition”:true,”authors”:[{“id”:323,”name”:{“display”:”Hrefna Palsdottir, MS”,”first”:”Hrefna”,”last”:”Pálsdóttir”},”userLogin”:”hpalsdottir”,”links”:{“website”:””,”facebook”:””,”linkedin”:””,”twitter”:””,”instagram”:””,”tiktok”:””},”email”:”hpalsdottir@example.com”,”type”:{“value”:”author”,”label”:”Author”},”nid”:”126235″,”specialties”:[],”bio”:{},”avatar”:{“title”:””,”width”:210,”height”:210,”src”:”https://post.healthline.com/wp-content/uploads/2018/09/hrefna-palsdottir.png”}}],”reviewedByHeader”:”By”},{“title”:[“10 of the Best Probiotics for Women in 2023 According to a Dietitian”],”text”:[“If you’re interested in starting probiotic supplements, consider trying one of these 10 probiotics for women’s health.”],”link”:”/health/food-nutrition/best-probiotics-women”,”imageAlt”:”10 of the Best Probiotics for Women in 2023 According to a Dietitian”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2023/01/2738408-Clone-Market-nutrition-10-of-the-Best-Probiotics-for-Women-in-2023-A-Dietitians-Picks-732×549-Thumbnail-732×549.jpg”,”isNutrition”:false,”authors”:[{“id”:270,”name”:{“display”:”Rachael Ajmera, MS, RD”,”first”:”Rachael”,”last”:”Ajmera, MS, RD”},”userLogin”:”rachaellink1″,”links”:{“website”:”http://nutrimental.co”,”facebook”:””,”linkedin”:”https://www.linkedin.com/in/rachael-ajmera-ms-rd-975760b9/”,”twitter”:””,”instagram”:”https://www.instagram.com/nutrimental”,”tiktok”:””},”link”:”/authors/rachael-link”,”email”:”rachaellink1@gmail.com”,”type”:{“value”:”author”,”label”:”Author”},”nid”:”126218″,”specialties”:[],”guestTitle”:””,”bio”:{“text”:” Rachael Ajmera, MS, RD is a registered dietitian and health writer who is passionate about plant-based nutrition and achieving better health by balancing time between the kitchen and the gym. Rachael completed her undergraduate degree at the University of Central Missouri and received her master’s degree from New York University. You can learn more on her website or follow her on Instagram and LinkedIn.n”},”avatar”:{“title”:””,”width”:500,”height”:500,”src”:”https://post.healthline.com/wp-content/uploads/2021/11/Racheal-Link-500×500-Bio.png”}}],”reviewedByHeader”:”Medically reviewed by”},{“title”:[“8 Health Benefits of Probiotics”],”text”:[“Probiotics can improve your health. 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Rachael completed her undergraduate degree at the University of Central Missouri and received her master’s degree from New York University. You can learn more on her website or follow her on Instagram and LinkedIn.n”},”avatar”:{“title”:””,”width”:500,”height”:500,”src”:”https://post.healthline.com/wp-content/uploads/2021/11/Racheal-Link-500×500-Bio.png”}}],”reviewedByHeader”:”Medically reviewed by”},{“title”:[“How Do You Use “,{“tagName”:”em”,”source”:”Lactobacillus bulgaricus”},”?”],”link”:”/health/digestive-health/lactobacillus-bulgaricus”,”imageAlt”:”How Do You Use Lactobacillus bulgaricus?”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2020/08/732x549_THUMBNAIL_Lactobacillus_Bulgaricus-1-732×549.jpg”,”medicallyReviewedBy”:{“reviewerName”:”Natalie Butler, R.D., L.D.”,”reviewerImage”:{“path”:”https://post.healthline.com/wp-content/uploads/2018/09/NatalieButler.png”,”width”:200,”height”:200,”altText”:””},”specialties”:[]},”isNutrition”:false,”authors”:[{“id”:1423,”name”:{“display”:”Neel Duggal”,”first”:”Neel”,”last”:”Duggal”},”userLogin”:”nduggal”,”links”:{“website”:””,”facebook”:””,”linkedin”:””,”twitter”:””,”instagram”:””,”tiktok”:””},”email”:”nduggal@example.com”,”type”:{“value”:”author”,”label”:”Author”},”bio”:{},”avatar”:{“title”:””,”src”:””}}],”reviewedByHeader”:”Medically reviewed by”},{“title”:[“There’s Little Evidence That Probiotics Help Most GI Symptoms”],”text”:[“A new guideline by the American Gastroenterological Association cautions that there’s not enough scientific evidence to recommend using these…”],”link”:”/health-news/theres-little-evidence-that-probiotics-help-most-gi-symptoms”,”imageAlt”:”There’s Little Evidence That Probiotics Help Most GI Symptoms”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2020/06/Probiotics_732x549-thumbnail-732×549.jpg”,”isNutrition”:false,”authors”:[{“id”:26,”name”:{“display”:”Shawn Radcliffe”,”first”:”Shawn”,”last”:”Radcliffe”},”userLogin”:”sradcliffe”,”links”:{“website”:””,”facebook”:””,”linkedin”:””,”twitter”:”ShawnRadcliffe”,”instagram”:””,”tiktok”:””},”link”:”/authors/shawn-radcliffe”,”email”:”shawn.radcliffe@gmail.com”,”type”:{“value”:”author”,”label”:”Author”},”nid”:””,”specialties”:false,”guestTitle”:””,”bio”:{“text”:” Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.n”},”avatar”:{“title”:””,”width”:500,”height”:500,”src”:”https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png”}}],”reviewedByHeader”:”Medically reviewed by”},{“title”:[“Do Probiotics Need to Be Refrigerated?”],”text”:[“Probiotics come in both refrigerated and shelf-stable varieties. 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You can learn more on her website or follow her on Instagram and LinkedIn.n”},”avatar”:{“title”:””,”width”:500,”height”:500,”src”:”https://post.healthline.com/wp-content/uploads/2021/11/Racheal-Link-500×500-Bio.png”}}],”reviewedByHeader”:”By”},{“title”:[“What Are the Most Common Types of Probiotics?”],”text”:[“Learn about six of the most common types of probiotics and why they’re called “good” bacteria.”],”link”:”/health/types-of-probiotics”,”imageAlt”:”What Are the Most Common Types of Probiotics?”,”thumbnail”:”https://post.healthline.com/wp-content/uploads/2020/08/What_Are_the_Most_Common_Types_of_Probiotics-732×549-thumbnail-1-732×549.jpg”,”medicallyReviewedBy”:{“reviewerName”:”Saurabh Sethi, M.D., MPH”,”reviewerImage”:{“path”:”https://post.healthline.com/wp-content/uploads/2022/01/Saurabh-Sethi-500×500-Bio.png”,”width”:200,”height”:200,”altText”:””}},”isNutrition”:false,”authors”:[{“id”:186,”name”:{“display”:”Marjorie Hecht”,”first”:”Marjorie”,”last”:”Hecht”},”userLogin”:”marjehecht”,”links”:{“website”:””,”facebook”:””,”linkedin”:””,”twitter”:””,”instagram”:””,”tiktok”:””},”link”:”/authors/marjorie-hecht”,”email”:”marjehecht@gmail.com”,”type”:{“value”:”author”,”label”:”Author”},”nid”:”159206″,”specialties”:false,”guestTitle”:””,”bio”:{“text”:” Marjorie Hecht is a longtime magazine editor/writer, now working as a freelancer on Cape Cod. Her specialties are science, technology, and medicine, but her eclectic career includes being a reporter at the United Nations and covering politics in Washington, D.C. She has an MSW from Columbia University, a BA from Smith College, and she did postgraduate work in race and demography at the London School of Economics.n”},”avatar”:{“title”:””,”src”:””}}],”reviewedByHeader”:”Medically reviewed by”}]}})})() ]]>n
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Nutrition
We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission or other tangible benefit. Optum Store, Optum Perks, and Healthline Media are owned by RVO Health. Here’s our process.
Healthline only shows you brands and products that we stand behind.
Our team thoroughly researches and evaluates the recommendations we make on our site. To establish that the product manufacturers addressed safety and efficacy standards, we:- Evaluate ingredients and composition: Do they have the potential to cause harm?
- Fact-check all health claims: Do they align with the current body of scientific evidence?
- Assess the brand: Does it operate with integrity and adhere to industry best practices?
Our dietitians rounded up the best probiotic supplements for a variety of needs, including weight loss, allergies, IBS, and general use. Culturelle ranks as our best overall pick, but read on for other options.
Probiotics are among the most popular dietary supplements, and sales of them continue to skyrocket each year.
People may take probiotics to help reduce symptoms of certain medical conditions, bolster their immune health, improve depressive symptoms, and even promote weight loss.
Not everyone needs to take a probiotic supplement, but if you and your healthcare team decide that you may benefit from taking one, there are many excellent products on the market to choose from.
This article features our picks of the 11 best probiotic supplements on the market. It also explains what probiotic supplements are, who may benefit from taking one, and how to choose the right product for your needs.
The World Health Organization has defined probiotics as “live microorganisms that, when administered in adequate amounts, confer a health benefit on the host”.
Probiotics are found naturally in certain foods, such as kimchi and fermented yogurt. They are also found in your gut, where they participate in a variety of important bodily processes, such as vitamin production, mood regulation, digestion, and immune function.
Probiotics are also available in supplement form. These supplements contain high doses of either a single probiotic strain or multiple probiotic strains.
Probiotic supplements have been linked to some health benefits. But, while research on probiotics has increased significantly over the past 20 years, researchers are still learning about them and their health effects.
What are CFUs?
Probiotics are generally measured in colony-forming units (CFUs). These units represent the number of viable bacteria per dose.
Products labeled “1 x 109 CFU” contain 1 billion viable or live bacteria per dose. Most supplements contain 1–10 billion CFUs per dose, but some contain much larger amounts.
To confer beneficial effects, probiotics must be taken in quite large doses. Researchers suggest that probiotics must contain at least 106 (1 million) viable CFUs per gram to be able to survive digestion and exert positive effects in the body.
We selected the best probiotics using the following criteria:
- Vetting: All the products have been vetted to ensure that they meet Healthline’s medical and business standards, adhere to Food and Drug Administration (FDA) regulations on allowable health claims and labeling requirements, and are manufactured in facilities that adhere to Current Good Manufacturing Practices (CGMPs) established by the FDA.
- Credibility: The products we chose are made by medically credible companies that follow ethical, legal, and industry best standards and that provide objective measures of trust, including having supplements thoroughly tested for purity and potency, ideally by third-party organizations.
- Effective dose: With the exception of one product (which doesn’t use CFUs), all the supplements below contain at least 106 (1 million) CFUs per gram.
- Ingredients: We looked for products that are made from high quality ingredients and free of artificial additives and fillers.
- Personal needs: We included options to suit a variety of needs and preferences, whether you need a specific probiotic strain or you follow a gluten-free diet.
- Dose: 1 capsule per day
- Certifications: none
- Shelf-stable: yes
- Price: $$
Healthline‘s review
Culturelle is a well-known brand of probiotics and is one of the best overall probiotic supplements thanks to its formulation and high CFU count. Plus, it doesn’t need to be refrigerated.
One capsule of Culturelle Digestive Daily Probiotic has 10 billion CFUs of Lactobacillus rhamnosus GG, a probiotic strain that may benefit a number of health conditions, such as diarrhea and irritable bowel syndrome (IBS).
This supplement also contains 200 milligrams (mg) of the prebiotic inulin, which fuels beneficial gut bacteria.
Culturelle guarantees that the stated number of CFUs on the box is viable through the expiration date of the product, something the National Institutes of Health (NIH) recommends customers look out for.
While products are not routinely tested for purity and potency by a third-party lab, the company states that it takes multiple measures to ensure quality and safety.
Additionally, Culturelle probiotics have been used in multiple clinical studies, and the company’s processes are audited regularly by NSF International.
- may be good for diarrhea and IBS
- doesn’t need refrigeration
- gluten-free and dairy-free
- rigorous quality and safety standards
- packaged to ensure CFU count until end of shelf life
- contains clinically studied strains
- not third-party tested for purity and potency
- may not be suitable for those following a vegan diet
- Form: capsule
- Number of servings: 30 per container
- Strains: Lactobacillus rhamnosus GG
- CFU count: 10 billion
Best probiotic supplement for women
- Dose: 1 capsule per day
- Certifications: none
- Shelf-stable: yes
- Price: $$
Healthline‘s review
Each serving of Culturelle 4-in-1 Protection contains 15 billion CFUs of the probiotic strains Lactobacillus rhamnosus GG, Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus gasseri LBV 150, and Lactobacillus jensenii LBV 116, all of which are important for women’s health.
Lactobacillus rhamnosus GG promotes healthy digestion, while the rest of the included stains, such as Lactobacillus gasseri, benefit vaginal and urinary health.
These strains help keep your vaginal bacteria population healthy and may also help protect against urinary tract infections by preventing the invasion of potentially harmful pathogens and encouraging a balanced environment in the vagina and urinary tract.
The supplement also includes a proprietary blend of prebiotics.
You can find more of our picks of the best probiotics for women here.
- supports vaginal and urinary health
- doesn’t need refrigeration
- gluten-free and dairy-free
- rigorous quality and safety standards
- packaged to ensure CFU count until end of shelf life
- contains clinically studied strains
- includes prebiotics
- not third-party tested for purity and potency
- may not be suitable for those following a vegan diet
- Form: capsule
- Number of servings: 30 per container
- Strains: Lactobacillus crispatus LBV 88, Lactobacillus rhamnosus LBV 96, Lactobacillus rhamnosus GG, Lactobacillus gasseri LBV 150N, Lactobacillus jensenii LBV 116
- CFU count: 15 billion
Best probiotic supplement for IBS
- Dose: 1 capsule per day
- Shelf-stable: yes
- Certifications: none
- Price: $$$
Healthline‘s review
Align is a physician-trusted brand that contains Bifidobacterium longum 35624, formerly known as Bifidobacterium infantis 35624, a probiotic strain that has been researched for its role in digestive health, including IBS symptoms.
This product’s label states that each capsule contains 5 billion live bacteria at the time of manufacturing and 50 million CFUs until the “best by” date.
Because it doesn’t require refrigeration, it’s a good option if you travel often or prefer not to worry about storing your probiotic supplement in the fridge.
Note that Align contains trace amounts of lactose, so it may not be appropriate for those with severe lactose intolerance.
According to the company, Align Probiotic is DNA tested to confirm that it contains Bifidobacterium longum 35624. However, it’s unclear whether testing is performed in-house or by a third-party organization.
- travel-friendly
- formulated to relieve digestive issues
- contains a clinically tested strain
- DNA tested to confirm identity
- may not be appropriate for those with lactose intolerance
- not suitable for vegan diets
- expensive
- unclear whether product is third-party tested for purity and potency
- Form: capsule
- Number of servings: 21 per container
- Strains: Bifidobacterium longum subsp. longum
- CFU count: 5 billion
Best probiotic supplement for men
- Dose: 1–2 capsules once or twice per day
- Certifications: Vegetarian Society Approved, non-GMO
- Shelf-stable: yes
- Price: $$
Healthline‘s review
Bio-Kult contains 14 probiotic strains that may be beneficial for men’s health, including Lactobacillus acidophilus, Streptococcus thermophilus, and Bifidobacterium longum.
Additionally, some research suggests that supporting a healthy microbiome by taking a high quality probiotic supplement, such as Bio-Kult, may help protect against prostate cancer, the most common form of cancer among men in the United States.
Each Bio-Kult capsule contains a minimum of 2 billion microorganisms, and Bio-Kult guarantees that the total bacteria count is viable until the end of the product’s shelf life.
Each probiotic strain in Bio-Kult is microencapsulated and individually freeze-dried. This protects the probiotics from stomach acid and allows the product to be stored at room temperature.
Bio-Kult is not appropriate for those with a severe allergy to milk proteins, but it is safe for those with lactose intolerance.
- stored at room temperature
- relatively affordable
- suitable for all ages
- supports men’s health
- not appropriate for those with severe allergy to milk proteins
- not suitable for vegan diets
- unclear whether product is third-party tested for purity and potency
- Form: capsule
- Number of servings: 30, 60, or 120 per container
- Strains: Bacillus subtilis PXN 21, Bifodobacterium bifidum PXN 23, Bifidobacterium breve PXN 25, Bifidobacterium infantis PXN 27, Bifidobacterium longum PXN 30, Lactobacillus acidophilus PXN 35, Lactobacillus delbrueckii ssp. bulgaricus PXN 39, Lactobacillus casei PXN 37, Lactobacillus plantarum PXN 47, Lactobacillus rhamnosus PXN 54, Lactobacillus helveticus PXN 45, Lactobacillus salivarius PXN 57, Lactococcus lactis ssp. lactis PXN 63, Streptococcus thermophilus PXN 66
- CFU count: 2 billion
Best affordable probiotic supplement
- Dose: 2 capsules per day
- Certifications: third-party tested for purity and potency
- Shelf-stable: yes
- Price: $
Healthline‘s review
Jarrow Formulas Jarro-Dophilus EPS contains eight probiotic species from six genera: Lactobacillus, Bifidobacterium, Lacticaseibacillus, Lactiplantibacillus, Lactococcus, and Pediococcus.
It’s also one of the most affordable options.
The capsules have an enteric coating, which is a barrier that helps minimize degradation in the stomach.
Some studies show that enteric-coated probiotics are more effective than non-enteric-coated probiotics. A 2019 study found that enteric coating led to a 20‐ to 40‐fold increase in the delivery of viable probiotics to the small intestine.
If the product is stored properly — at room temperature in a cool, dry environment — the 5 billion CFU count per capsule is guaranteed through the “best used before” date.
Jarrow Formulas products are tested by third-party labs that are accredited by the U.S. Department of Agriculture (USDA).
- no refrigeration necessary
- third-party tested for purity and potency
- relatively affordable
- not suitable for vegan diets
- Form: capsule
- Number of servings: 60 or 30 per container
- Strains: Lacticaseibacillus rhamnosus, Lactobacillus helveticus, Pediococcus acidilactici, Lacticaseibacillus casei, Bifidobacterium longum, Lactiplantibacillus plantarum, Bifidobacterium breve, Lactococcus lactis subsp. lactis
- CFU count: 10 billion
Best probiotic supplement for weight loss
- Dose: 1 capsule per day
- Certifications: non-GMO verified, certified NSF Gluten-Free, third-party tested for purity and potency
- Shelf-stable: no
- Price: $$$
Healthline‘s review
Research shows that people who are overweight are more likely to have dysbiosis (an imbalance in gut bacteria) and lower bacterial diversity than people who are not. This may increase hunger and increase energy storage in fat tissues, which contributes to weight gain.
Taking a probiotic supplement containing specific probiotic strains, such as Lactobacillus gasseri, L. rhamnosus, and L. plantarum, may help promote weight loss in several ways, including by decreasing gut permeability, reducing inflammation, and increasing bacterial diversity.
Garden of Life Dr. Formulated Probiotics Once Daily, 30 Billion CFUs provides 30 billion CFUs of 14 probiotic strains, including Lactobacillus gasseri and L. rhamnosus, which could help support weight loss.
Garden of Life guarantees the CFU count through the end of the product’s “best use” date if it’s stored properly. This supplement keeps best in the refrigerator.
According to the company, Garden of Life supplements are third-party tested. However. the company does not disclose the name of the testing organization.
- CFU count guaranteed through best-use date when product is stored properly
- dairy-free
- contains strains that may promote weight loss
- third-party tested for purity and potency
- not suitable for travel, as it requires refrigeration
- expensive
- not suitable for those with severe food allergies
- not vegan-friendly
- Form: capsule
- Number of servings: 30 per container
- Strains: Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus gasseri, Lactobacillus paracasei, Bifidobacterium lactis, Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum
- CFU count: 30 billion
Best allergy-friendly probiotic supplement
- Dose: 1 capsule, once or twice per day
- Certifications: CGMP certified, Strain Verified, UL Solutions Certified
- Shelf-stable: yes
- Price: $$
Healthline‘s review
NOW Probiotic-10 25 Billion is a blend of 10 probiotics, including Lactobacillus acidophilus, Bifidobacterium lactis, and Lactobacillus rhamnosus. Many of the strains it contains have been shown to support immune health.
This product is formulated to deliver a potency of at least 25 billion CFUs through the “best by” date.
NOW uses DNA fingerprinting technology to guarantee the identity, potency, and purity of the bacterial strains used in its probiotic products. This testing also helps identify potential bacterial contaminants in the products prior to manufacturing.
Additionally, NOW’s facilities are certified by UL Solutions (previously Underwriters Laboratories), an independent certification safety company that ensures safe manufacturing and storage practices.
This probiotic is processed in an allergen-free facility, so it’s suitable for those with allergies.
- processed in an allergen-free facility
- UL Solutions-certified
- delivers a potency of at least 25 billion CFUs through the best-by date
- uses DNA fingerprinting technology
- may support a strong immune system
- not suitable for vegan diets
- Form: capsule
- Number of servings: 30, 50, or 100 per container
- Strains: Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus paracasei, Bifidobacterium breve, Streptocous thermophilus, Lactobacillus salivarius, Bifidobacterium longum
- CFU count: 25 billion
Best pre- and probiotic supplement
- Dose: 1 capsule, once or twice per day
- Shelf-stable: yes
- Certifications: Monash University Low FODMAP Certified, NSF Certified
- Price: $$$
Healthline‘s review
Klaire Labs Ther-Biotic Pro contains a blend of probiotics and a prebiotic.
Specifically, it contains Lactobacillus and Bifidobacterium probiotic strains, both of which have been shown to help relieve IBS-related symptoms such as abdominal pain, constipation, and diarrhea, though more research is still needed.
It also includes partially hydrolyzed guar gum, a prebiotic that feeds the good bacteria in your gut. A 2019 study found that 5 grams of partially hydrolyzed guar gum was effective `in improving stool form in adults with IBS-D over the course of 12 weeks, but more research is needed.
This product is free from common allergens, though it’s unclear whether there’s a risk of cross-contamination.
Additionally, the supplement doesn’t require refrigeration, but storing it in the refrigerator may extend its shelf life.
Klaire Labs products are processed in a facility that follows the CGMPs put in place by the FDA and is certified by NSF International.
- contains probiotics and prebiotics
- contains strains that may help manage IBS symptoms
- does not require refrigeration
- free from allergens
- NSF Certified
- expensive
- not suitable for vegan diets
- not suitable for people who don’t tolerate prebiotics well
- Form: capsule
- Number of servings: 21 or 42 per container
- Strains: Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus plantarum
- CFU count: 20 billion
Best probiotic supplement for athletes
- Dose: 1 capsule, once or twice per day
- Certifications: NSF Certified for Sport
- Shelf-stable: yes
- Price: $$$
Healthline‘s review
Thorne FloraSport 20B contains 20 billion CFUs from 3 probiotic strains. It’s formulated specifically for individuals who are under stress, such as athletes, as it’s meant to support both the digestive and immune systems.
While exercise has many benefits, engaging in regular high intensity workouts can take a toll on your body’s immune response.
This probiotic from Thorne contains Lactobacillus acidophilus and Bifidobacterium lactis, both of which have been shown to support immune health and could be beneficial for athletes and other active individuals.
Refrigeration isn’t required, as the capsules are packaged in temperature-resistant blister packs, making this a great option for traveling.
Additionally, this probiotic supplement is certified gluten-free and NSF Certified for Sport — a third-party certification that ensures products are free of substances banned in competitive sports.
- packaged in temperature-resistant blister packs — no refrigeration required
- formulated for athletes, active individuals, and travelers
- NSF Certified for Sport
- expensive
- may not be suitable for those following a vegan diet
- Form: capsule
- Number of servings: 30 per container
- Strains: Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus paracasei
- CFU count: 20 billion
Best probiotic supplement for diarrhea
- Dose: 2 capsules, once or twice per day
- Shelf-stable: yes
- Certifications: none
- Price: $$$
Healthline‘s review
Each capsule of Florastor Daily Probiotic provides 250 mg of Saccharomyces boulardii, a probiotic yeast that may be effective in managing symptoms of inflammatory bowel disease (IBD).
The strain has also been shown to help with diarrhea, especially antibiotic-associated or acute diarrhea (15, 16).
At time of publish, Florastor Daily Probiotic has a 4.7 out of 5-star rating on Amazon and more than 9,000 total reviews. Customers note that the probiotic is effective for reducing gas and bloating, though many also feel that it’s a bit too expensive.
The supplement comes in a vegetarian capsule and is non-GMO and gluten-free. However, because it contains lactose, it’s not suitable for those who have a dairy allergy.
It’s unclear whether these probiotics are tested to ensure purity and potency. While Florastor doesn’t mention third-party testing on the company’s website, the product is sold by CVS, which requires third-party testing on all of its dietary supplements.
- high customer rating
- no refrigeration required
- contains probiotic strain that may be helpful for antibiotic-associated and acute diarrhea
- not appropriate for those with an allergy to milk proteins
- unclear if third-party tested for purity and potency
- Form: capsule
- Number of servings: 27 or 50 per container
- Strains: Saccharomyces boulardii
- CFU count: 250 mg of Saccharomyces boulardii CNCM I-745
Best probiotic subscription
- Dose: 1 capsule per day
- Shelf-stable: yes
- Certifications: third-party tested for purity and potency, Non-GMO Project Verified, Made Traceable
- Price: $$$
Healthline‘s review
Ritual is a subscription-based supplement company best known for its multivitamins. However, the company also offers Synbiotic+, a probiotic that stands out from others on the market because it contains pre-, pro-, and postbiotics.
Postbiotics are bioactive compounds that bacteria secrete, often through fermentation. While postbiotics are believed to offer some health benefits, research on the subject is limited.
Ritual’s Synbiotic+ contains probiotic strains, such as Lactobacillus rhamnosus, that may be beneficial for people with IBS, though more research is needed.
The company conducted a test-tube study that suggested Synbiotic+ could support gut barrier function and increase the growth of beneficial bacteria. But keep in mind that because Ritual funded the study, there is a risk of bias.
“I’ve struggled with digestive issues for years and was excited to try out Synbiotic+ as a possible replacement for the expensive pre- and probiotics that I was taking.
“I’ve been taking the supplement for 3 weeks and haven’t experienced an adjustment period or negative side effects. So far, it seems to be helping with my bloating, and the pills’ minty-fresh flavor is fantastic.
“Overall, I’ve had a great experience and will be replacing my old supplements with Ritual Synbiotic+”
— Christy Snyder, Editor II
Read more about Ritual in our expert review.
- third-party tested for purity and potency
- vegan-friendly
- no refrigeration required
- delayed-release capsule design
- good for people interested in a pre-, pro-, and postbiotic
- not suitable for people who don’t tolerate prebiotics well
- Form: capsules
- Number of servings: 30 per container
- Strains: Lactobacillus rhamnosus LGG, Bifidobacterium animalis ssp. lactis BB-12
- CFU count: 11 billion
Here’s a quick look at how our top picks compare:
Probiotic supplements have been shown to benefit health in a number of ways.
However, some of the purported benefits of probiotics aren’t supported by research, so it’s important to always consult a healthcare professional before taking a probiotic supplement, especially if you’re hoping to improve symptoms related to a health condition.
May improve symptoms of certain gastrointestinal conditions
Some of the most well-studied uses of probiotic supplements relate to the treatment of gastrointestinal conditions such as IBS and IBD.
In one review of 11 studies, 7 of the studies reported significant improvements in symptoms such as bloating and abdominal pain in people with IBS who took probiotic supplements, compared with a placebo. The remaining four studies didn’t find significant improvements.
The review also found that multistrain probiotics used for at least 8 weeks were the most effective for improving IBS symptoms.
Notably, Lactobacillus acidophilus was present in all of the multistrain supplement studies that reported significant improvements.
Multistrain probiotics may improve some symptoms in those with IBD, though they appear to be less effective for people with Crohn’s disease. However, evidence is currently limited and well-designed studies are needed.
May help with constipation and diarrhea
Studies indicate that probiotics may help improve multiple types of diarrhea, including infectious diarrhea, antibiotic-associated diarrhea, and traveler’s diarrhea.
Certain strains, including Lactobacillus rhamnosus GG and Saccharomyces boulardii, seem to be particularly effective for treating diarrhea in children and adults.
Some probiotics, such as Bifidobacterium lactis, may also help improve constipation. However, study results vary, with some showing no improvements in constipation with probiotic treatment.
May benefit urinary health
Supplementing with probiotics may help maintain urinary tract health and be beneficial for women who get frequent urinary tract infections (UTIs).
Some studies show that treatment with the probiotics Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 may help reduce UTIs in women.
However, study results are conflicting.
One review of three randomized controlled trials found that taking probiotics didn’t significantly reduce UTI recurrence in postmenopausal women.
Other potential benefits
In addition to the benefits listed above, some research suggests that probiotic supplements may have the following effects:
- May promote immune health: Evidence supports the role of probiotic supplements in maintaining immune health. Several studies suggest that probiotics may enhance immune function in certain populations, but more research is needed.
- May benefit metabolic health and weight management: Alterations in gut bacteria may contribute to obesity and metabolic issues, and some studies have shown that probiotic supplements may promote weight loss. Research in this area is ongoing.
- May improve cardiovascular risk factors: Probiotic supplements may help reduce blood lipid levels in some people, which may decrease the risk of heart disease. However, evidence is limited at this time.
- May help treat certain mood and emotional disorders: Studies suggest that certain probiotics may help reduce symptoms of depression and anxiety, but more high quality studies are needed before strong conclusions can be made.
If you’re interested in taking a probiotic supplement, it’s important to first determine whether a probiotic supplement is necessary for your specific health needs.
If you’re instructed to take a probiotic, please consider the following:
- Probiotic strains: Probiotics are not one-size-fits-all remedies, and certain probiotic strains are much more effective for certain medical conditions and symptoms than others. Look for supplements with specific strains based on your needs.
- Intended use: The effectiveness of probiotic supplements is not only strain-specific but also disease-specific, meaning the correct strain and dose must be appropriate for the condition or symptom you intend to treat.
- Brand: Manufacturing processes, shelf life, and formulation type can significantly affect a probiotic supplement’s effectiveness. Therefore, it’s essential to buy probiotics from established, physician-trusted brands.
- Storage requirements: Some probiotics require refrigeration. Check the product label for proper storage instructions. In general, probiotics are sensitive to heat. Thus, if they don’t require refrigeration, you’ll want to store them in a cool, dry area.
- CFUs: The product quality matters. It’s important to look for probiotics that contain at least 106 (1 million) CFUs per gram, as research suggests that this is the minimum amount needed to exert positive effects in the body.
Also keep in mind that because probiotics are quite vulnerable to factors such as temperature change and storage time, many may no longer be viable by the time you purchase them.
For this reason, the NIH recommends that customers choose products that list the CFUs at the end of a product’s shelf life. This indicates that a product contains a therapeutic number of CFUs after the product is purchased.
Contrary to popular belief, probiotic supplements are not necessary or appropriate for most people.
Not only can they be expensive, but they may lead to side effects such as bloating and bacterial overgrowth. Plus, they could lead to excessive immune stimulation and infection among people with weakened immune systems.
While some people, including those with IBS and certain types of IBD, may benefit from specific strains of probiotics, in general, most healthy people who follow a nutritious diet and healthy lifestyle do not need to take probiotic supplements.
What’s more, some researchers are concerned that the widespread use of probiotics may lead to antibiotic resistance and warn that many studies investigating the safety and effectiveness of probiotics are of poor quality.
For these reasons, it’s not a good idea to take probiotics before consulting a healthcare professional. They can help you decide whether a probiotic supplement is appropriate and give brand and dosage recommendations.
If you’re experiencing gastrointestinal symptoms such as abdominal pain, bloating, cramping, diarrhea, and constipation; have received a diagnosis of IBD or IBS; or are concerned about your vaginal health, you may benefit from a probiotic.
But it’s a good idea to schedule an appointment with a healthcare professional first, because your symptoms could be related to a condition that requires a specific treatment or medication.
Additionally, taking a probiotic can do more harm than good in some individuals, so it’s important to discuss options with a trusted expert before trying anything new.
What is the most effective form of probiotic?
Research suggests that probiotics must contain at least 106 (1 million) viable CFUs per gram to have a clinically significant effect. Additionally, the most-studied and most-used strains of probiotics are Lactobacillus and Bifidobacterium.
However, probiotic supplements are strain- and disease-specific, so the most effective strain will depend on the condition or issue that the supplement is meant to improve.
What is the most effective probiotic supplement?
Because probiotics are strain-, disease-, and symptom-specific, no single probiotic is more effective overall than others. An effective probiotic supplement contains one or more probiotic strains that have been clinically shown to help with the symptoms you’re experiencing.
Still, some brands are considered to offer higher quality probiotic supplements, including Culturelle, Align, Bio-Kult, and Jarrow Formulas.
Is it OK to take a probiotic every day?
Because research on the safety and effectiveness of probiotics in people without existing health conditions is still inconclusive, it’s best to talk with a healthcare professional before starting a daily probiotic.
Probiotic supplements may be helpful for people with certain conditions, such as IBS, constipation, and UTIs.
However, probiotics aren’t necessary for everyone, and the effectiveness of probiotic supplements depends on the strain, dosage, and condition being treated.
Finally, there are many other ways to take care of your gut microbiome and overall health that don’t involve dietary supplements, including following a nutrient-dense diet, managing your stress levels, and maintaining a moderate weight.
Last medically reviewed on May 16, 2023
How we reviewed this article:
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ncbi.nlm.nih.gov/pmc/articles/PMC5995450/
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Jul 18, 2023
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May 16, 2023
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